If you are traveling, you need to remember that your puppy is not fully vaccinated and needs to avoid any place where unvaccinated dogs may have been.  If you have to use a rest area, drive to the very remotest part and carry your puppy to the back of the area.  Do not let them wander around.

Please keep in mind that bringing home a new puppy is always a very exciting and special day that you will always remember. For puppy it is the day he left his littermates, so even though it is the beginning of the best part of his life, it can be terrifying day of changes and unfamiliar faces and smells. Try to reduce stress by making his drive home as calm and quiet as possible. Make sure he goes to the bathroom before getting in the car. You could put him in his crate, but a small and quiet puppy can be carried in a blanket by a family member or friend. Make sure you talk to him all the way home.